Indicates an individual's ability to metabolize and detoxify alcohol, guiding reasonable and healthy drinking
Reveals a high-risk tendency for major diseases
Mutations in Alcohol Metabolite genes can increase the risk of diseases such as esophageal cancer, oral cancer, stomach cancer, coronary heart disease, and myocardial infarction. Conducting Alcohol Metabolite Test helps in early detection and early prevention.
Guides the rational clinical use of nitroglycerin
ALDH2 is closely related to the clinical efficacy of nitroglycerin. Patients with the ALDH2 gene mutation have an ineffective rate of over 25% when taking nitroglycerin. It is recommended that patients undergo ALDH2 gene testing before using nitroglycerin. Patients with ALDH2 gene mutations should use nitroglycerin with caution or consider alternative medications.
Applicable Population for Alcohol Metabolite Test
Long-term drinkers
Individuals who drink alcohol regularly due to work requirements or personal hobbies.
Coronary heart disease patients
Patients with coronary heart disease or angina who are long-term users of nitroglycerin.
Individuals with a family history of hereditary diseases
Those with a family history of diseases such as hepatitis B, digestive system diseases, cardiovascular diseases, and endocrine system diseases.
Sub-healthy population
Individuals with poor lifestyle habits such as excessive drinking and staying up late, as well as those under high work pressure and frequent tension.
Healthy individuals
Health-conscious individuals.
Alcohol Metabolite Test
Simply put, Alcohol Metabolite Test involves a series of genes related to the breakdown of alcohol. When alcohol enters human body, it is metabolized by the liver. The metabolism process of alcohol in the human body is: ethanol → acetaldehyde → acetic acid → carbon dioxide and water. Ethanol, acetic acid, carbon dioxide, and water are relatively safe, but the troublesome intermediate product is acetaldehyde. Aldehyde dehydrogenase, encoded by the ALDH2 gene, can metabolize acetaldehyde into relatively safe acetic acid, preventing the toxic accumulation of acetaldehyde. Thus, the ALDH2 gene is crucial.
Understanding Your Alcohol Metabolite Test Report
If your report result is GG, congratulations, it indicates strong alcohol metabolism ability and good enzyme activity, meaning you have a strong ability to detoxify alcohol and can drink alcohol in moderation. If it is GA, the metabolism ability is relatively weak, some enzymes are active, and detoxifying alcohol is difficult, so you should control your alcohol intake. If it is AA, the metabolism ability is poor, the enzyme is completely inactive, and detoxifying alcohol is very difficult, so it is best not to drink.
Alcohol Metabolite Test requires just one tube of blood and is simple and convenient to check. Based on the ALDH2 genotype test result, individuals who need to drink can predict their risk of getting drunk, the risk of acetaldehyde accumulation (a class I carcinogen), and the risk of cirrhosis and cancer. This allows effective management of alcohol intake and drinking frequency.
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